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| FLUVOXAMINE MALEATE | |||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 54739-18-3
(Base) 61718-82-9 (Maleate) |
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| EINECS NO. | |||
| FORMULA | C15H21O2N2F3·C4H4O4 | ||
| MOL WT. | 434.41 | ||
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H.S. CODE |
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TOXICITY |
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| SYNONYMS | LuVox; Faverin; | ||
| 5-methoxy-4'-(trifluoromethyl) valerophenone-(E)-O-(2-aminoethyl)oxime maleate (1:1); | |||
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | white to off-white crystalline powder | ||
| MELTING POINT | 120 - 123 C | ||
| BOILING POINT |
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| SPECIFIC GRAVITY |
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| SOLUBILITY IN WATER | sparingly soluble | ||
| pH | |||
| VAPOR DENSITY |
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REFRACTIVE INDEX |
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NFPA RATINGS |
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AUTOIGNITION |
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FLASH POINT |
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| STABILITY | Stable under normal conditions | ||
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GENERAL DESCRIPTION & APPLICATIONS |
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Fluvoxamine is a drug of Selective
Serotonin Reuptake Inhibitor (SSRI) which interferes
with serotonin ((chemically 5-hydroxytryptamine, 5-HT) transport, used to treat
depression, anxiety, obsessive-compulsive disorders (OCD), eating disorders, and
social phobias. Fluvoxamine is considered to cause less loss of sex-drive and
other side effects than other SSRIs. Examples of SSRI include Fluoxetine (Prozac, Fontex),
Paroxetine (Paxil, Seroxat), Sertraline (Zoloft), Escitalopram Oxalate
(Lexapro), Citalopram (Celexa), Fluvoxamine Maleate (Luvox), Bupropion
(Wellbutrin). SSRIs have been increasingly replacing cyclic antidepressants
which have been the most common antidepressants due to less side effects and to
minimize suicide attempt. Examples of tricyclic antidepressants include
Amitriptyline (Elavil,Endep), Clomipramine (Anafranil), Desipramine (Norpramin,
Pertofrane), Doxepin (Adapin, Sinequan), Imipramine (Tofranil), Nortryptyline
(Pamelor), Protriptyline (Vivactil), Trimipramine (Surmontil) and tetracyclic
antidepressant is Maprotiline (Ludiomil). |
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| SALES SPECIFICATION | |||
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BP/USP/CP |
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IDENTITY |
pass |
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ASSAY |
98.5 - 101.0% |
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LOSS ON DRYING |
1.0% max |
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RESIDUE ON IGNITION |
0.5% max |
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VOLATILE IMPURITY |
pass |
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HEAVY METALS |
20ppm max |
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| TRANSPORTATION | |||
| PACKING | | ||
| HAZARD CLASS | |||
| UN NO. | |||
| OTHER INFORMATION | |||
| Hazard Symbols: XI, Risk Phrases: 20/21/22, Safety Phrases: 36 | |||
| PRICES | |||
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